Tuesday, 27 March 2018

Prince toxicology:report indicates he had excessively high levels of the drug fentanyl in his system

A toxicology report from Prince's autopsy, obtained Monday by the Associated Press, shows he had what multiple experts called an "exceedingly high" concentration of fentanyl in his body when he died.
Prince was 57 when he was found alone and unresponsive in an elevator at his Paisley Park estate on April 21, 2016. Public data released six weeks after his death showed he died of an accidental overdose of fentanyl, a synthetic opioid 50 times more powerful than heroin.
A confidential toxicology report obtained by the AP provides some insight into just how much fentanyl was in his system. Experts who are not connected to the Prince investigation said the numbers leave no doubt that fentanyl killed him.
"The amount in his blood is exceedingly high, even for somebody who is a chronic pain patient on fentanyl patches," said Dr. Lewis Nelson, chairman of emergency medicine at Rutgers New Jersey Medical School. He called the fentanyl concentrations "a pretty clear smoking gun."
The report says the concentration of fentanyl in Prince's blood was 67.8 micrograms per liter. The report explains that fatalities have been documented in people with blood levels ranging from three to 58 micrograms per liter.
The report also says the level of fentanyl in Prince's liver was 450 micrograms per kilogram, and notes that liver concentrations greater than 69 micrograms per kilogram "seem to represent overdose or fatal toxicity cases."
There was also what experts called a potentially lethal amount of fentanyl in Prince's stomach. Dr. Charles McKay, president of the American College of Medical Toxicology, said generally speaking, the findings suggest Prince took the drug orally, while fentanyl in the blood and liver suggest it had some time to circulate before he died.
Experts say there is no "lethal level" at which fentanyl can kill. A person who takes prescription opioids for a long time builds up a tolerance, and a dose that could kill one person might curb pain for another.
Search warrants released about a year after Prince's death showed authorities found numerous pills in various containers around his home. A lab report obtained by the AP shows many of the pills tested positive for fentanyl and other drugs. Information that has been released publicly indicates the source of those drugs hasn't been determined.
Last week, the lead prosecutor in Carver County, the Minnesota county where Prince died, said in a statement that he was reviewing law enforcement reports and would make a decision on whether to charge anyone "in the near future."
Last week, the lead prosecutor in Carver County, the Minnesota county where Prince died, said in a statement that he was reviewing law enforcement reports and would make a decision on whether to charge anyone "in the near future."

A toxicology report reveals the amount of the drug fentanyl in Prince's system when he died.
A newly-discovered report gives a much clearer picture as to Prince’s cause of death in 2016.
According to a toxicology report obtained by the Associated Press from Prince’s autopsy, he had what experts call an “exceedingly high” concentration of fentanyl in his body at the time of his death. For those unfamiliar, fentanyl is a synthetic opioid that is said to be 50 times more powerful than heroin.
Prince was found dead in an elevator at his Paisley Park estate and many were curious if drugs played a role in the famed musician’s demise. News that he had the drug in his system is not new, as that information came to light roughly six weeks after his death. However, the new confidential report gives a bit of scope as to how much he was dealing with when he died.
Experts say the amount in his system was high, even for someone suffering from chronic pain. The report notes that he had 67.8 micrograms per liter in his system. Fatalities from the drug have been documented in people with blood levels ranging anywhere from three to 58 micrograms per liter.
The report also says the level of fentanyl in Prince's liver was 450 micrograms per kilogram, and notes that liver concentrations greater than 69 micrograms per kilogram "seem to represent overdose or fatal toxicity cases."
Based on findings of the drug in his stomach and blood, it’s clear that he took the drug orally and had enough time for it to spread into his system a bit before he died. Reports from the time of Prince’s death indicated that police found multiple bottles of pills around his residence and that the origin of those pills was still undetermined.
The Associated Press contributed to this report.
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